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- 2018
MerTK as a therapeutic target in glioblastomaKeywords: glioblastoma, macrophage, MerTK, microenvironment Abstract: Glioma-associated macrophages and microglia (GAMs) are components of the glioblastoma (GBM) microenvironment that express MerTK, a receptor tyrosine kinase that triggers efferocytosis and can suppress innate immune responses. The aim of the study was to define MerTK as a therapeutic target using an orally bioavailable inhibitor, UNC2025
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