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- 2019
TrkB expression and dependence divides gustatory neurons into three subpopulationsDOI: 10.1186/s13064-019-0127-z Keywords: BDNF, TrkB, Neurotrophin, Taste, Geniculate ganglion, Taste buds, Innervation, Neuron development, Gustatory Abstract: Half of adult taste neurons express the TrkB receptor. a) Representative image of the entire z-stack of a whole mount adult geniculate ganglion from a Phox2b-Cre::tdTomato::TrkBGFP/+ mouse labeled for both tdTomato (oral cavity-projecting, red) and GFP (TrkB, green). b) Quantification of the total number of neurons (n =?3) projecting to the oral cavity (red only) and oral cavity-projecting neurons that express TrkBGFP (double-labeled). c-e) Magnified images of a single optical section illustrate the criteria used to identify and count single-labeled (arrowhead) and double-labeled (arrow) oral cavity-projecting neurons. Scale bar?=?50?μm (a) and 10?μm (c-e). ***p <?0.00
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