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-  2019 

More than myelin: Probing white matter differences in prematurity with quantitative T1 and diffusion MRI

DOI: 10.1016/j.nicl.2019.101756

Keywords: Preterm, Corpus callosum, Fractional anisotropy, Development, myelin AD, axial diffusivity, CP, Cerebral palsy, CC, corpus callosum, dMRI, diffusion MRI, FA, fractional anisotropy, FT, full term, GA, gestational age, MD, mean diffusivity, PT, preterm, RD, radial diffusivity, qt1, quantitative T1

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Abstract:

We combined diffusion MRI (dMRI) with quantitative T1 (qT1) relaxometry in a sample of school-aged children born preterm and full term to determine whether reduced fractional anisotropy (FA) within the corpus callosum of the preterm group could be explained by a reduction in myelin content, as indexed by R1 (1/T1) from qT1 scans

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