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-  2018 

An assessment of prognostic immunity markers in breast cancer

DOI: 10.1038/s41523-018-0088-0

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Abstract:

RNA-seq gene expression of 17 immunity genes and 19 proliferation genes in published PBMC single-cell dataset (Macosko et al. Cell 2015)26 and breast cancer solid tumor single cells (Chung et al. Nature Communications 2017).27 (A) Expression of immunity and proliferation genes in different PBMC cell types including B cells, CD4 T cells, CD8 T cells, NK cells, Monocytes and dendritic cells. (B) Expression of immunity and proliferation genes of single cells including breast tumors’ immune single cells labeled as T_cell?+?Mac?+?M & B_cell (Mac?=?macrophages, M?=?monocytes) and carcinoma single cells groups 1 to 3 (mixed carcinoma single cells from different tumors), BC02 and BC05 (carcinoma single cells from each individual tumor

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