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- 2019
Ribosomal RNA genes shape chromatin domains associating with the nucleolusDOI: 10.1080/19491034.2019.1591106 Keywords: Chromatin, genome organization, nucleolus, rRNA genes Abstract: Genomic interactions can occur in addition to those within chromosome territories and can be organized around nuclear bodies. Several studies revealed how the nucleolus anchors higher order chromatin structures of specific chromosome regions displaying heterochromatic features. In this review, we comment on advances in this emerging field, with a particular focus on a recent study published by Quinodoz et al., that developed a new method to characterize simultaneous genomic interactions in the same cell. Highlighting studies conducted in animal and plant cells, we then discuss the establishment of inactive chromatin at nucleolus organizer region (NOR)-bearing chromosomes
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