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- 2017
SLE and Serum Complement: Causative, Concomitant or Coincidental?DOI: 10.2174/1874312901711010113 Keywords: SLE, Systemic Lupus Erythematosus, SLE flares', Complement, CB-CAPS Abstract: Systemic Lupus Erythematosus (SLE) is an incurable autoimmune disorder with complement activation playing a key role in the pathogenesis of immune-mediated tissue injury. While quantifying complement to monitor SLE disease activity has been the standard of care since the 1950s, decreased complement levels are not consistently associated with flares
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