Prospects for strain-specific immunotherapy in Alzheimer’s disease and tauopathies

Immunotherapeutic approaches targeting amyloidogenic seeds and secondary amyloidosis thus, preventing disease progression. a A representation of the current view of the relationship between tau and Aβ toxic species, which are being targeted by passive immunotherapy. b Recent research suggests that effective immunotherapies may require targeting multiple strains/conformers formed by different amyloidogenic protein