Cell division cycle associated 5 promotes colorectal cancer progression by activating the ERK signaling pathway

a CDCA5 mRNA in tissues from 50 CRC patients, as analyzed by q-PCR. GAPDH was used as internal control. b CDCA5 protein in 73 pairs of CRC tissues and adjacent normal tissues, as determined by IHC-based tissue microarray. Image magnification at ×40 or ×200. T: tumor tissues; N: normal tissues. *P？<？0.05, tumors vs. normal tissues. c, d CDCA5 mRNA in the R2 Bioinformatic Platform (c) and TCGA (d). *P？<？0.05, tumors vs. normal tissues. e CDCA5 mRNA and f CDCA5 protein in a panel of CRC cell lines and FHC cells, as determined by q-PCR and Western-blot analyses. GAPDH was used as the internal control. n？=？3. *P？<？0.05, vs. FHC cells. Data are shown as mean？±？S