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- 2019
Preliminary evidence that hydroxyurea is associated with attenuated peripheral sensitization in adults with sickle cell diseaseDOI: 10.1097/PR9.0000000000000724 Keywords: Sickle cell disease, Hydroxyurea, Quantitative sensory testing, VOC pain, Chronic pain Abstract: Hydroxyurea (HU) is a drug that targets the underlying pathophysiology of sickle cell disease (SCD); however, it continues to be an underutilized treatment for adults. Previous research suggests that HU treatment can result in fewer hospital contacts for acute vaso-occlusive pain crises (VOC). Hydroxyurea's impact on non-VOC pain, however, is not well established
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