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- 2019
Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathwaysDOI: 10.1097/PR9.0000000000000718 Keywords: Disk herniation, Inflammation, Growth factors, Epiregulin, EREG Abstract: Lumbar radicular pain after disk herniation is associated with local release of many inflammatory molecules from nucleus pulposus (NP) cells leaking out of the intervertebral disk. Here, we have used a rat model to investigate the role of epiregulin (EREG), a member of the epidermal growth factor (EGF) family, in this process
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