Long-term survival and swallowing outcomes in advanced stage oropharyngeal squamous cell carcinomas
DOI: 10.1016/j.pvr.2018.09.002
Keywords: ACR , Alberta Cancer Registry , CI , confidence interval , CRT , chemoradiation , CCI , Charleson comorbidity index , DSS , disease specific survival , ENE , extranodal/extracapsular extension , ECOG , European Consortium Oncology Group , G-tube , gastrostomy tube , HPV , human papillomavirus , HPV-OPSCC , human papillomavirus-related oropharyngeal squamous cell carcinoma , HR , hazard ratio , IHC , immunohistochemistry , IMRT , intensity modulated radiation therapy , LOHS , length of hospital stay , LVI , lymphovascular invasion , NCCN , National Comprehensive Cancer Network , OPSCC , oropharyngeal squamous cell carcinoma , OS , overall survival , PEG , percutaneous endoscopic gastrostomy , PNI , perineural invasion , RT , radiation therapy , S+RT/CRT , primary surgery with post-operative radiation or chemoradiation , VFSS , videofluoroscopic swallowing study
Abstract:
There is a paucity of studies reporting long-term survival outcomes for HPV/p16 positive oropharyngeal squamous cell carcinoma (OPSCC). This study aims to compare long-term outcomes of advanced stage p16 positive and negative OPSCCs, treated by surgical and non-surgical modalities
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