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- 2017
Non-invasive Raman Spectroscopy and Quantitative Real-Time PCR Distinguish Among Undifferentiated Human Mesenchymal Stem Cells and Redifferentiated Nucleus Pulposus Cells and Chondrocytes In VitroDOI: 10.2174/1874120701711010072 Keywords: Intervertebral disc regeneration, Mesenchymal stem cells, Nucleus pulposus cells, Chondrocytes, Characterization, Distinction, Cell markers, Raman spectroscopy Abstract: The most common cause of lower back pain is the pathological degeneration of the nucleus pulposus (NP). Promising NP regeneration strategies involving human mesenchymal stem cells (hMSCs) would require specific markers to confirm successful differentiation into the NP lineage and to distinguish the articular cartilage (AC)
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