|
- 2019
HPV16 variant analysis in primary and recurrent CIN2/3 lesions demonstrates presence of the same consensus variantDOI: 10.1016/j.pvr.2019.04.008 Keywords: Whole-genome sequencing, HPV16, HPV genome variants, CIN, rCIN, Recurrent infection Abstract: Recurrent cervical intraepithelial lesions (rCIN2/3) after treatment of CIN2/3 occur in 5–15% of cases. rCIN2/3 can result from incomplete resection of CIN2/3, where the same HPV type and variant remains present. rCIN2/3 could also occur following a new infection with a different HPV variant of the same HPV type as the initial lesion. This study investigates HPV16 consensus variants in paired HPV16 positive scrapes from baseline CIN2/3 and rCIN2/3 lesions
|