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- 2019
Epitope targeting with self-assembled peptide vaccinesDOI: 10.1038/s41541-019-0125-5 Keywords: Biotechnology, Immunology Abstract: P8 peptide forms a heat stable trimeric coiled-coil. a Circular dichroism spectra: P8 was dissolved in phosphate-buffered saline and subjected to increasing temperature from 5?°C to 95?°C, followed by a return to 5?°C (gray line). b Analytical ultracentrifugation spectrum of P8 showing monomer (0.76?S), trimer (1.78?S), and higher-order assemblies (>3?S). c Intensity-weighted dynamic light scattering spectrum showing major self-assembly (7?nm) and two minor assemblies (25 and 350?nm
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