A Single Intraperitoneal Injection of Endotoxin Changes Glial Cells in Rats as Revealed by Positron Emission Tomography Using [11C]PK11195

Endotoxin-induced inflammation affects glial cells. a A single intraperitoneal injection of endotoxin induced significant changes in [11C]PK11195 SUV in the bilateral frontal regions and the striata. The results are drawn on the normalized MRI images derived from individual images. b, c Color atlases of these slices. The numbers indicate the ROIs: 1 olfactory bulb, 2 neocortex, 3 striatum, 4 hippocampal formation, 5 thalamus, 6 corpus callosum and associated subcortical white matte