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- 2019
Free fatty acid-induced histone acetyltransferase activity accelerates lipid accumulation in HepG2 cellsDOI: 10.4162/nrp.2019.13.3.196 Keywords: Histone acetyltransferases, lipogenesis, non-alcoholic fatty liver disease, lipid metabolism, HepG2 cell Abstract: Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disease triggered by epigenetic alterations, including lysine acetylation at histone or non-histone proteins, affecting the stability or transcription of lipogenic genes. Although various natural dietary compounds have anti-lipogenic effects, their effects on the acetylation status and lipid metabolism in the liver have not been thoroughly investigated
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