Wernicke’s Encephalopathy 5 Years After a Whipple Procedure

A 54-year-old Hispanic man presented with progressive generalized weakness and gait unsteadiness resulting in multiple falls over the course of 5 days. Over the preceding 2 weeks, he noted mental slowing and difficulty concentrating. Prior to this, he recalls having recurrent vomiting for a few days with diarrhea. He had a Whipple procedure for pancreatic cancer 5 years earlier. He drank socially leading up to his diagnosis of pancreatic cancer but was abstinent since. On examination, his level of alertness was slightly reduced; he was unable to determine the date but knew the month and year, and he was unable to correctly identify the hospital but he knew he was not at home. He could recall 2 of 3 objects after a 3-minute delay. His language was fluent and speech was not dysarthric. He had bidirectional gaze-evoked nystagmus but no ophthalmoparesis. The remainder of his cranial nerve motor and sensory examinations was unremarkable. Deep tendon reflexes were +3 throughout, except both ankles were +2. Plantar reflexes were downgoing. There was slight ataxia with finger-nose-finger testing and more obvious ataxia with heel-knee-shin testing bilaterally. He was able to stand with assistance but had marked truncal ataxia preventing any further gait testing