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- 2016
A Novel Way of Treating Multidrug-resistant EnterococciKeywords: Daptomycin/beta (β)-lactam, daptomycin nonsusceptibility, vancomycin-resistant enterococci Abstract: Daptomycin is the only antibiotic available with in vitro bactericidal activity against vancomycin-resistant enterococci (VRE). Its increased use has resulted in cases of decreased daptomycin efficacy. Recent in vitro studies have shown effective use of beta (β)-lactam and daptomycin antibiotics, as a combination therapy, in the treatment of VRE. We describe a case of effective treatment in a patient with VRE infection using dual ampicillin and daptomycin therapy that shows bench-to-bedside application of the abovementioned finding
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