Now is the Critical Time for Engineered Neuroplasticity

Repeated pairing of natural spiking activity with stimulation (left) leads to long-term changes in connections between the trigger neuron (red) and the stimulated site (green) that persist for 10 days (center). This is likely due to strengthening of synaptic connections between the trigger and stimulated locations (right) [7]. Reprinted by permission from Springer-Nature, long-term motor cortex plasticity induced by an electronic neural implant, Jackson et al., COPYRIGHT 200