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- 2017
Urine metabolic ratio of omeprazole in relation to CYP2C19 polymorphisms in Russian peptic ulcer patientsDOI: 10.2147/PGPM.S141935 Keywords: pharmacogenetics, phenotyping, metabolomics, proton pump inhibitor Abstract: CYP2C19 is known to be the main enzyme of biotransformation of proton pump inhibitors (PPIs), whereas the CYP2C19 gene is highly polymorphic. Genotyping and phenotyping together represent more reliable data about patient’s CYP2C19 activity
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