Effectiveness and cost-effectiveness of a multicomponent intervention to improve medication adherence in people with depressive disorders – MAPDep: a study protocol for a cluster randomized controlled trial

Depression is a widespread mental disorder which can be treated effectively. However, low adherence to antidepressants is very common. The study of medication adherence in depression (MAPDep study) assesses the effectiveness and cost-effectiveness of a multicomponent strategy to enhance adherence toward medications in patients with depression