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-  2017 

Annonacin Exerts Antitumor Activity through Induction of Apoptosis and Extracellular Signal-regulated Kinase Inhibition

DOI: 10.4103/pr.pr_19_17

Keywords: Annona muricata, apoptosis, caspase-3, cell cycle arrest, extracellular signal-regulated kinase, uterine cancer

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Abstract:

Endometrial cancer (EC) is the most common gynecologic malignancy in developed countries. Annonacin, a natural pure compound extracted from the seeds of Annona muricata, is a potential alternative therapeutic agent to treat EC

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