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-  2018 

Cytotoxic Compounds from Wrightia pubescens (R.Br.)

DOI: 10.4103/pr.pr_45_17

Keywords: Apocynaceae, chlorophyll a, cytotoxicity, half maximal inhibitory concentration, HCT-116, HT-29, HDFn, MCF-7, oleanolic acid, PrestoBlue? cell viability assay, squalene, ursolic acid, Wrightia pubescens R. Brown, wrightiadione, α-amyrin acetate

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Abstract:

Mixtures of ursolic acid (1) and oleanolic acid (2) (1:1 and 1:2), oleanolic acid (2), squalene (3), chlorophyll a (4), wrightiadione (5), and α-amyrin acetate (6) were isolated from the dichloromethane (CH2 Cl2) extracts of the leaves and twigs of Wrightia pubescens (R.Br.)

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