In vivo tracking of orally-administered particles within the gastrointestinal tract of murine models using multispectral optoacoustic tomography

While particle carriers have potential to revolutionize disease treatment, using these carriers requires knowledge of spatial and temporal biodistribution. The goal of this study was to track orally administered particle uptake and trafficking through the murine gastrointestinal (GI) tract using multispectral optoacoustic tomography (MSOT)