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- 2018
Applying dynamic contrast enhanced MSOT imaging to intratumoral pharmacokinetic modelingDOI: 10.1016/j.pacs.2018.07.003 Keywords: Pharmacokinetic modeling, Targeted contrast agent, Intratumoral kinetics, Tumor microenvironment, Hypoxia, Multispectral optoacoustic imaging Abstract: Examining the dynamics of an agent in the tumor microenvironment can offer critical insights to the influx rate and accumulation of the agent. Intratumoral kinetic characterization in the in vivo setting can further elicudate distribution patterns and tumor microenvironment
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