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-  2019 

Correlation of regional deposition dosage for inhaled nanoparticles in human and rat olfactory

DOI: 10.1186/s12989-019-0290-8

Keywords: Inhalation toxicity, Neurotoxicity, Nanoparticles, Nasal olfactory, Olfactory pathway, Olfactory deposition, Human and rat interspecies extrapolation

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Abstract:

Human and rat nasal and olfactory model: (a) upper respiratory airways, olfactory brain pathways, and particle release profile; (b) 2D unwrapped nasal cavity surface model. (Brain images: Univ ersity of Calgary, 2006 (human), The Scientist, 2015 (rat)); (c) sample cross section of nasal and olfactory channe

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