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- 2018
Biomarkers Associated with Death After Initiating Treatment for Tuberculosis and HIV in Patients with Very Low CD4 CellsKeywords: Mycobacterium tuberculosis, Human Immunodeficiency Virus, Timing of antiretroviral therapy, Predictors of mortality, Nutrition biomarkers, Innate immunity, Adaptive immunity Abstract: The risk of short-term death for treatment naive patients dually infected with Myco-bacterium tuberculosis and HIV may be reduced by early anti-retroviral therapy. Of those dying, mechanisms responsible for fatal outcomes are unclear. We hypothesized that greater malnutrition and/or inflammation when initiating treatment are associated with an increased risk for death
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