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-  2019 

The impact of the Glasgow Prognostic Score on survival in second-line chemotherapy for metastatic colorectal cancer patients with BRAF V600E mutation

DOI: 10.1177/1758835918820298

Keywords: BRAF V600E mutation, Glasgow Prognostic Score, metastatic colorectal cancer, second-line chemotherapy

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Abstract:

BRAF (v-raf murine sarcoma viral oncogene homolog B1) V600E mutant colorectal cancer is associated with short survival. Recently, clinical trials have been conducted to improve outcomes of second or later lines of chemotherapy. However, there is a paucity of reference data pertaining to outcomes of second-line chemotherapy and prognostic factors that are relevant only to BRAF mutant patients

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