|
- 2019
Pharmacokinetics and safety of deltoid or gluteal injection of aripiprazole lauroxil NanoCrystal? Dispersion used for initiation of the long-acting antipsychotic aripiprazole lauroxilKeywords: ALNCD, antipsychotic, aripiprazole lauroxil, aripiprazole, bioavailability, initiation regimen, injection site, long-acting injectable, pharmacokinetics, safety/tolerability Abstract: Aripiprazole lauroxil (AL), a long-acting injectable antipsychotic for the treatment of schizophrenia in adults, can be started with either 21?days of daily oral aripiprazole supplementation or a 1-day initiation regimen consisting of a single injection of a NanoCrystal? Dispersion formulation of AL (ALNCD) and a single dose of 30?mg oral aripiprazole. This phase I study assessed the pharmacokinetics and safety of deltoid versus gluteal ALNCD injections
|