|
- 2019
AllergoOncology: High innate IgE levels are decisive for the survival of cancer-bearing miceDOI: 10.1016/j.waojou.2019.100044 Keywords: AllergoOncology, Cancer vaccine, IgE, HER-2, Onco-immunology ADCC, Antibody-dependent Cell-mediated Cytotoxicity, ADCP, Antibody-dependent Cellular Phagocytosis, BCR, B-Cell Receptor, HER-2, Human Epidermal Growth Factor Receptor-2, ErbB-2, IgA, Immunoglobulin A, IgE, Immunoglobulin E, IgG, Immunoglobulin G, TAA, Tumor-Associated Antigen, WT, wild type Abstract: Atopics have a lower risk for malignancies, and IgE targeted to tumors is superior to IgG in fighting cancer. Whether IgE-mediated innate or adaptive immune surveillance can confer protection against tumors remains unclear
|