|
- 2018
Architecture of the RNA polymerase II elongation complex: new insights into Spt4/5 and Elf1DOI: 10.1080/21541264.2018.1454817 Keywords: RNA polymerase II, transcription elongation, elongation complex, Spt4/5, Elf1, TFIIS, X-ray crystallography, cryo-EM Abstract: Transcription by RNA polymerase II (Pol II) is accomplished with the aid of numerous accessory factors specific to each transcriptional stage. The structure of the Pol II elongation complex (EC) bound with Spt4/5, Elf1, and TFIIS unveiled the sophisticated basal EC architecture essential for transcription elongation and other transcription-related events
|