Anti-melanogenic and anti-oxidant activities of ethanol extract of Kummerowia striata: Kummerowia striata regulate anti-melanogenic activity through down-regulation of TRP-1, TRP-2 and MITF expression

DOI: 10.1016/j.toxrep.2018.11.005

Keywords: L-DOPA, L-3,4-dihydroxyphenylalanine, TRP-1, tyrosinase-related protein 1, MITF, microphthalmia-associated transcription factor, ABTS, 2,2？-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt, DPPH, l 2,2-diphenyl-1-picrylhydrazyl, EKS, ethanol extract of K. striata, DMEM, Dulbecco’s Modified Eagle Medium, FBS, fetal bovine serum, COSY, correlation spectroscopy, HSQC, heteronuclear single quantum coherence, HMBC, heteronuclear multiple bond correlation, ESI, electrospray ionization, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide, DMSO, dimethyl sulfoxide, α-MSH, α-Melanocyte-stimulating hormone, BHA, butylated hydroxyanisole, RT-PCR, reverse transcription-polymerase chain reaction, SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis Kummerowia striata, Anti-oxidant, Melanin, p-coumaric acid, Quercetin

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