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-  2019 

1H NMR-based metabolomic study of metabolic profiling for pollinosis

DOI: 10.1016/j.waojou.2018.11.005

Keywords: Pollinosis, Metabonomics, Energy, Amino acid, Lipid metabolism NMR, nuclear magnetic resonance, SIT, allergen-specific immunotherapy, PBS, phosphate buffer solution, TSP, 3-trimethylsilyl-propionic acid, PCA, principle component analysis, OPLS-DA, orthogonal partial least squares discriminant analysis, OSC-PLS-DA, orthogonal signal correction-partial least squares discriminant analysis, FIDs, free induction decay, SD, standard deviation, TCA, tricarboxylic acid cycle, SLE, systemic lupus erythematosus

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Abstract:

Allergic rhinitis is the main symptom of pollinosis, relieved by non-specific treatment universally. This study aimed to find the changes of serum metabolites between the seizure and remission periods of pollinosis and provide assistance in the diagnosis and/or therapy

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