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-  2019 

Abundance of mitochondrial superoxide dismutase is a negative predictive biomarker for endometriosis-associated ovarian cancers

DOI: 10.1186/s12957-019-1565-0

Keywords: Clear cell ovarian carcinoma, Endometrioid ovarian carcinoma, Endometriosis-associated ovarian cancer, Mitochondrial superoxide dismutase

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Abstract:

Examples of mitochondrial superoxide dismutase (SOD2) expression in endometriosis-associated ovarian cancers on immunohistochemical analysis. Cases subjected to immunohistochemical analysis for detection of mitochondrial superoxide dismutase (SOD2) expression in clear cell carcinoma and endometrioid carcinoma are shown in (a, c) and (b, d), respectively. High and low mitochondrial superoxide dismutase (SOD2) expression levels are demonstrated in (a, b) and (c, d), respectively. Green arrowheads indicate stromal cell areas, where SOD2 was subtly expressed and used as internal controls. The scale bars correspond to 100?μ

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