The need to develop personalized interventions to improve cognition in schizophrenia

Green et al1 provide a review of the evidence on neurocognitive and social cognitive deficits in schizophrenia. These deficits span the course of the disease, starting from the prodrome, and are stable over time. Impairments in neurocognition involve learning and memory, vigilance/attention, speed of processing, reasoning and problem solving, and working memory. Social cognition deficits affect psychological processes implicated in the perception, encoding, storage, retrieval and regulation of information about other people and ourselves. The underlying neurobiological disturbances have their origin in brain networks involving the hippocampus as well as temporal, parietal and prefrontal cortex. Here we discuss the central role of the hippocampus in cognitive processes and the impact of non‐pharmacological treatments on this brain structure in schizophrenia patients