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-  2019 

Clinical utility of basophil activation test in diagnosis and predicting severity of mugwort pollen-related peach allergy

DOI: 10.1016/j.waojou.2019.100043

Keywords: Basophil activation test, Peach extract, Pru p 3, Mugwort pollen allergy, Peach allergy BAT, basophil activation test, LTP, lipid transfer protein, sIgE, specific IgE, DBPCFC, double-blind placebo-controlled food challenge, SPT, skin prick testing, OAS, oral allergy syndrome, SR, systemic reaction, ROC, receiver operating characteristic, AUC, area under the curve, SABA, short-acting β2-agonist

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Abstract:

Cross-reactivity between pollen and plant foods results in low specificity of food-IgE and skin prick testing, which may cause over-diagnosis. A test that can accurately diagnose pollen-related food allergy and identify patients at risk of developing severe reactions is needed. This study evaluates basophil CD63 expression as a biomarker for diagnosis and predicting severity of mugwort pollen-related peach allergy

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