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-  2018 

In Vivo Observation of Endothelial Cell-Assisted Vascularization in Pancreatic Cancer Xenograft Engineering

DOI: 10.1007/s13770-018-0113-2

Keywords: Cancer tissue engineering, Vascularization, Patient-derived xenograft, Pancreatic cancer

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Abstract:

Schematic diagram of the pancreatic cancer xenograft engineering. Four experimental groups were prepared according to embedded cell and sample conditions: (1) control with no cells in the fibrin (CON), (2) endothelial cells homogeneously distributed in the fibrin (EH), (3) endothelial cells homogeneously distributed with the cancer aggregate located in the center of the fibrin (EHCA), (4) endothelial cells and cancer cells homogeneously distributed in the fibrin (EHCH

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