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Theranostics 2018
Aptamer-functionalized nanoscale metal-organic frameworks for targeted photodynamic therapyDOI: 10.7150/thno.26768 Keywords: nanoscale metal-organic frameworks, aptamer, G-quadruplex, TMPyP4, photodynamic therapy Abstract: Photodynamic therapy (PDT) has been applied in clinical cancer treatment. Here we report an aptamer-functionalized nanoscale metal-organic framework for targeted PDT. Our nanosystem can be easily prepared and successfully used for targeted PDT with a significantly enhanced therapeutic efficacy in vitro and in vivo.
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