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Theranostics  2018 

MicroRNA-193b-3p regulates chondrogenesis and chondrocyte metabolism by targeting HDAC3

DOI: 10.7150/thno.23547

Keywords: microRNA-193b-3p, HDAC3, histone acetylation, chondrogenesis, cartilage

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Abstract:

Histone deacetylase 3 (HDAC3) plays a pivotal role in the repression of cartilage-specific gene expression in human chondrocytes. The aim of this study was to determine whether microRNA-193b-3p (miR-193b-3p) regulates the expression of HDAC3 during chondrogenesis and chondrocyte metabolism.

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