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Additional Chemotherapy with 5-FU plus Leucovorin between Preoperative Chemoradiotherapy and Surgery Improved Treatment Outcomes in Patients with Advanced Rectal Cancer

DOI: 10.7150/jca.25366

Keywords: rectal cancer, preoperative therapy, chemotherapy, 5-fluorouracil (5-FU), leucovorin (LV)

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Abstract:

Purpose: The aim of the preliminary study was to evaluate the efficacy and safety of 4-week chemotherapy with 5-Fluorouracil and leucovorin (LV5FU2) during the resting periods between preoperative CRT and surgery in patients with LARC.

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