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Theranostics  2018 

WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma

DOI: 10.7150/thno.25025

Keywords: biomarker, glioblastoma, oncogene, prognosis, WNT6, WNT pathway

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Abstract:

Glioblastoma (GBM) is a universally fatal brain cancer, for which novel therapies targeting specific underlying oncogenic events are urgently needed. While the WNT pathway has been shown to be frequently activated in GBM, constituting a potential therapeutic target, the relevance of WNT6, an activator of this pathway, remains unknown.

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