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- 2019
Shortened up-dosing with sublingual immunotherapy drops containing tree allergens is well tolerated and elicits dose-dependent clinical effects during the first pollen seasonDOI: 10.1016/j.waojou.2019.100012 Keywords: Adherence, Asthma, Conjunctivitis, Immunotherapy, Pollen allergy, Pre-seasonal, Rhinitis, SLIT, Sublingual immunotherapy AE, adverse event, ARIA, Allergic Rhinitis and its Impact on Asthma, IgE, immunoglobulin E, N, number, PHD, Patient's Hay Fever Diary, RCAT, Rhinitis Control Assessment Test, SD, standard deviation, sIgE, specific immunoglobulin E, SLI, symptom load index, SLIT, sublingual immunotherapy, SmPC, Summary of Product Characteristics, TU, therapeutic units, V, visit Abstract: This study compared a rapid home-based up-dosing schedule for sublingual immunotherapy (SLIT) drops containing tree pollen allergens with two previously established schedules. Furthermore, the clinical effect of the SLIT was investigated with respect to patients’ first pollen season under treatment
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