Clinicopathological Features of Bladder Tumors in a Single Institution in Hyderabad, Sindh, Pakistan

Bladder carcinoma is one of the common urological malignancies occurring worldwide in both sexes. The clinical presentation of bladder cancer is classically with painless haematuria and dysuria. The vast majority of bladder tumours are epithelial in origin; of these a？？ 90% are TCCs, the remainder being squamous cell carcinoma, adenocarcinoma and mixed tumours. The purpose of this study was to determine the frequency of clinical and pathological features of Bladder Tumors, so that appropriate screening and preventive strategies could be developed to minimize the morbidity Objective: To determine the frequency of clinicopathological features of bladder tumors in patients presenting at University Hospital. Study Design: Descriptive Cross-sectional study. Setting: Department of Urology, Liaquat University of Medical and Health Sciences Jamshoro. Duration with dates: Six months from 7TH JANUARY 2013 TO 6TH JUNE 2013. Subjects and Methods: A total of 95 cases meeting inclusion criteria were enrolled in the study. The bladder specimens of all the patients were sent for histopathological examination to find out the nature and grade of the disease. Clinical factors like dysuria, urgency, hematuria, adenocarcinoma, TCC, SCC were noted in the proforma. Results: Mean (？±SD) age was 60.04 ？±10.3 years with M: F = 5.7: 1. Mean ？±SD duration of disease was 2.1 ？±1.3 years. Hematuria was found in 60 (72.6%) cases followed by dysuria in 36 (37.9%) cases and urine urgency in 21 (22.1%) cases. Transitional-cell carcinoma (TCC) seen in 86 (90.5%) of the cases. Squamous-cell and adenocarcinoma were found in 6 (6.3%) and 3 (3.2%) cases respectively. Conclusion: In this study painless macroscopic hematuria and histological sub-type transitional-cell carcinoma was dominant. Keywords: Bladder Tumor, Hematuria, Dysuria TCC, SCC, Adenocarcinom