Systemic inflammatory markers and sources of social support among older adults in the Memory Research Unit cohort

Potential associations between systemic inflammation and social support received by a sample of 120 older adults were examined here. Inflammatory markers, cognitive function, social support and psychosocial wellbeing were evaluated. A structural equation modelling approach was used to analyse the data. The model was a good fit χ 108 2 = 256 . 13 , p？<？0.001; comparative fit index？=？0.973; Tucker–Lewis Index？=？0.962; root mean square error of approximation？=？0.021; standardised root mean-square residual？=？0.074). Chemokine levels were associated with increased age (β？=？0.276), receipt of less social support from friends (β？=？？0.256) and body mass index (β？=？？0.256). Results are discussed in relation to social signal transduction theory