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Biophysics 2020
急性缺血性脑卒中治疗中直接抽吸除栓术的血流动力学计算机仿真研究进展
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Abstract:
在急性缺血性脑卒中的临床治疗中，直接抽吸除栓术作为一种新兴的微创介入治疗方法，在除栓效率、安全性、花费等方面相比于以前的方法均具有优势。为了促进直接抽吸除栓术在技术上的发展成熟，目前需要大力加强在对该技术所涉及的血流动力学机理的研究。本文回顾了当前应用计算机仿真对抽吸除栓过程进行血流动力学基础研究的相关进展，介绍和评注了文献中这方面研究的一系列研究工作，总结了当前工作所存在的问题，并对将来提出了具体的指导建议。
Among the clinical treatment options for the acute ischemic stroke, direct aspiration thrombectomy (DAT) as an emerging minimal invasive intervention technique has much advantage over the other treatment techniques, from the aspects of efficiency, safety, and procedure cost. To promote the technical maturity of DAT, it is important to strengthen study of the hemodynamics involved in DAT. This research reviewed the related concurrent hemodynamic studies of DAT using the computer simulation technique in the literature, introduced and commented on a series of studies in the field. The deficiencies of the current studies were summarized, and areas for future improvement sug-gested.
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