Obstacles and Impediments of Overweight and Obesity

Obesity is now pandemic, affecting millions of people in worldwide [1]. Obesity is defined as the excessive fat accumulation which may damage the health. Two groups of beneficial bacteria are dominant in the human gut, the Bacteroidetes and the Firmicutes. The relative proportion of Bacteroidetes is decreased in obese people by comparison with lean people and this proportion increases with weight loss on two types of low-calorie diet. Obesity has a microbial component which might have potential therapeutic implications [2]. Third National Health and Nutrition Examination Survey (NHANES III) provides the detailed population based overweight and obesity prevalence data [3]. Body mass index (BMI) is defined as a person’s weight in kilograms divided by the square of his height in meters (kg/m2). BMI provides the useful to measure of obesity and it is same for both sexes and for all ages. BMI value from 25 to 30 kg/m2 (overweight), 30 to 35 kg/m2 (obesity) points used by the World Health Organization (WHO) [4] and the National Institutes of Health (NIH) [5]. The basic cause of obesity is an energy imbalance between calories consumed and calories expended. Stevens et al. [6] viewing the burden of obesity showed that moderate obesity generally results in a 1 to 3-year reduction in life expectancy, depending on age. Obesity is a major cause of mortality [7] in the United States. Obesity substantially increases morbidity and impairs quality of life [8]. Metabolic clearance of Vitamin D may increase in obesity, possibly with enhanced uptake by adipose tissue [9]. Foetal macrosomia is more common in the obese non-diabetic mother compared to the lean mother with gestational diabetes [10]. Amino acids are insulin secretagogues and an increased flux on amino acids could stimulate foetal hyperinsulinemia. Triglycerides are energy rich and placental lipases can cleave triglyceride and transfer free fatty acids to the foetus [11]. Raised BMI is a major risk factor for cardiovascular diseases, diabetes, osteoarthritis and some cancers. Lower income people can afford more fat (from edible oils) and this upward shift in fat consumption is important for explaining part of the nutrition transition in China [12]. The increases in prevalence of overweight and obesity in Canada between 1985 and 2003 are cause for concern for increased risk of premature death and musculoskeletal complications arising from morbid obesity [13]. A large hip or thigh circumference or both, which could be due to a greater lean mass in the abdominal regions is negatively associated with all-cause