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-  2019 

Ultrasound and MRI measured changes in muscle mass gives different estimates but similar conclusions: a Bayesian approach

DOI: https://doi.org/10.1038/s41430-019-0431-z

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Abstract:

The purpose of this paper was to use a Bayesian approach to compare the relative change in muscle size between magnetic resonance imaging (MRI) and ultrasound measured muscle thickness (MTH) following 6 weeks of concentric and eccentric blood flow restricted exercise. Changes at each site were as follows: concentric 50% site (MRI: 10.2%, MTH: 8.7%), concentric 10?cm site (MRI: 12%, MTH: 4.5%), eccentric 50% site (MRI: ?1.7%, MTH: 2.6%), and eccentric 10?cm site (MRI: 5.2%, MTH: 0.5%). When testing the difference between estimates using a default prior of 0.707, we provided evidence that the estimate at the 50% site of the concentric arm was similar between ultrasound and MRI [Median % (95% credible interval): ?1.1 (?8.2, 5.8)]. However, evidence for other sites suggested differences or a degree of uncertainty. Both methods produce similar conclusions about the presence of growth but the magnitude of that change appears different at most sites

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