|
|
- 2019
Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA RepairDOI: https://doi.org/10.1016/j.ccell.2019.01.020 Abstract: ？ Phosphorylation of PTEN at tyrosine 240 (pY240) by FGFR2 mediates IR resistance ？ pY240-PTEN plays a critical role in DNA damage repair ？ pY240-PTEN associates with chromatin DNA through interaction with Ki-67 ？ Blocking pY240-PTEN using FGFR inhibitors sensitizes tumors to ionizing radiatio
|
