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- 2019
The Origin of CIMP, At LastDOI: https://doi.org/10.1016/j.ccell.2019.01.015 Abstract: In this issue of Cancer Cell, Tao et al. provide compelling evidence that aging-like DNA methylation of multiple CpG islands, the CpG island methylator phenotype (CIMP), produces a cellular context that can tolerate BRAF activation avoiding senescence by dedicating 5-month culture of colon-derived organoids to epigenomic and stemness analysis
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