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- 2019
Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 AxisDOI: https://doi.org/10.1016/j.ccell.2019.03.007 Abstract: ? Metformin plus fasting-induced hypoglycemia synergistically reduces tumor growth ? PP2A-GSK3β-MCL-1 axis mediates the synergistic cytotoxicity of the combination ? Simultaneous CIP2A inhibition and B56δ upregulation dictate combination specificit
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